陰惨[insan] sadness and gloom
惨い[mugoi] cruel
惨め[mijime] miserable
惨禍[sanka] calamity
惨害[sangai] heavy damage

惨劇[sangeki] tragedy
惨殺[zansatsu] slaughter
惨死[zanshi] tragic death
惨事[sanji] disaster
惨状[sanjou] disastrous scene

惨憺[santan] miserable
苦心惨憺[kushinsantan] taking great pains

意匠惨憺[ishousantan] taxing one's ingenuity in devising something